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Hyaluronic Acid

One of the most important biological functions of hyaluronic acid is to retain water, a role based on its capacity to hold more water than any other natural substance. Hyaluronic acid plays an important role in tissue hydration, lubrication and cellular function. Hyaluronic acid is used in some of the top selling commercial products such as Estee Lauder’s Night Repair Lotion and Lancome’s Activating Serum. However due to it’s high cost it is used in very small concentrations in these products. Hyaluronic acid has been shown to reduce dryness, itching and buring of the skin. Its unmatched hydrating properties result in increased smoothness, softening and decreased wrinkles.

Hyaluronic Acid is a major constituent of the extra-cellular matrix surronding rapidly dividing cells. Hyaluronic acid has been shown to be an integral componet in the rapid and scarless wound healing observed in fetal and neonatal organisms. The cellular actions precipitated by hyaluronic acid are integral to the seemingly magical biochemistry of fetal development. It is well documented that fetal tissues contain large amounts of hyaluronic acid and that decreasing hyaluronic acid content correlates with aging and wrinkling. Therefore practical attempts to prolong and recapture youth by revitalizing damaged tissue should include this molecule.

Hyaluronic Acid is naturally found in the joints, the deeper layers of skin, the umbilical cord and in fetal skin. Medical grade hyaluronic acid is currently employed to reduce the incidence of post operative adhesions, as a viscoelastic again in intraocular surgery and as a synovial replacement fluid. Hyaluronic acid offers an excellent environment for the growth of new cells and healing following skin peeling.

  1. Becker, Hilton, MD., Hartman, J.X. PhD., Shepard, S.M.S: Using hyaluronic acid to create a fetal like environment in vitro. Annals of Plasitic Surgery, Jan 1995
  2. Balaz, E.A., Band, P., Hyaluronic Acid: Its Structure and Use, Cosmetics and Toiletries, Vol 99, 65-81., June 1984
  3. P. Band: Biomatrix Inc., Ridgefield NJ, D and CI/October 1985
  4. R. Fleishemajer, J.S. Perlish and R.I. Bashley, 1972: Human Dermal Glycosamingoglycans and Ageing. Biochim. Biophys, ACTA, Vol 279, p. 265
  5. J.P. Pavlichko, Director of Technical Services Amercol Corp, Edison NJ. Drug and Cosmetic Industry, Oct 1985
  6. J.R. Yates, Mechanism of Water Uptake by Skin, in Biophysical Properties of the Skin. N.R. Eden, ed., Wiley Interscience, NY, 1971, p. 485

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