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JUVÉDERM™ Ultra and JUVÉDERM™ Ultra Plus The JUVÉDERM™ dermal filler family of products, approved by the U.S. Food and Drug Administration in 2006, is the next generation in hyaluronic acid dermal fillers that provide a smooth, long-lasting correction of moderate to severe facial wrinkles and folds.JUVÉDERM™ is the first smooth consistency gel formulation and is clinically proven to last up to one year. JUVÉDERM™ is developed using the proprietary HYLACROSS™ technology, an advanced manufacturing process that results in a malleable, smooth gel that flows easily into the skin and creates a smooth, natural look and feel. To provide physicians with the flexibility to tailor each treatment to the specific needs of the patient, there are two formulations of JUVÉDERM™. Product formulations include: JUVÉDERM™ Ultra, a highly cross-linked formulation for more versatility in contouring and volumizing of facial wrinkles and folds; and JUVÉDERM™ Ultra Plus, a more highly cross-linked and thicker gel for volumizing and correction of deeper folds and wrinkles.

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